Several neural systems of the mouse brain and their behavioural functions. Lesion studies and pharmacological approaches, combined with the analysis of genetically modified mice and of patients with brain lesions, have defined the brain systems that mediate specific behaviours. The hippocampus is crucial for spatial and contextual learning, whereas the amygdala is important for fear and anxiety. The hypothalamus mediates circadian rhythms, regulates sleep–wake cycles and is responsible for physiological homeostasis. The cerebellum is important for motor and procedural learning, as well as for motor coordination. By using appropriate behavioural tasks, the function of each of these neural systems can be examined in a mutant mouse.
Flair: Science
Collection: Biology Crash Course
